In a new double blind crossover trial, researchers found that even at a ratio of 3:1, CBD neither altered the subjective pleasurable effects of THC nor did it reduce adverse effects.
One of the biggest controversies in the cannabis field is whether CBD alters the physiological effects of THC. Many believe that CBD offsets some of the adverse effects of THC thereby making it more tolerable. And for sure, a number of studies have pointed towards such a possibility, especially where the ratio if CBD to THC is high.
Consequently, many believe that some of the adverse effects of THC can be “tamed” by adding CBD. While such a relationship can influence standards for safe THC limits, every effort needs to be made to ensure that such claims are substantiated.
In a recent study published in the journal Neuropsychopharmacology, researchers did not find any evidence that CBD prevents adverse effects that may be caused by THC. This led them to propose that the finding be considered in health policy decisions on medical and recreational cannabis.
This double blind crossover trial testing different THC: CBD ratios examined whether cannabidiol made cannabis safer.
The study included 46 healthy participants who were infrequent users of cannabis. The participants were offered vaporized cannabis with different concentrations of THC and CBD in four visits. The ratios offered were 1:1, 1:2, and 1:3 in a randomized and counterbalanced order. Even at a ratio…
