Medical cannabis use for severe childhood epilepsy may be linked to early pubertyPosted by On


The use of medical cannabis for severe childhood epilepsy may be linked to early puberty, doctors have warned in the journal BMJ Case Reports after treating a 2 year old boy with the condition.

Some previously published studies have linked cannabis use to increased levels of the male hormone testosterone, raising the question of a possible dose-related effect as higher strength preparations are readily available, the report authors point out.

Research suggests that cannabis oil may help cut the risk of seizures in childhood epilepsy. But as yet, there’s no consensus on its impact on a trio of glands, known as the hypothalamo-pituitary-gonadal (HPG) axis.

This trio is responsible for the development and regulation of several of the body systems, including those for reproduction.

The start of puberty before the age of 9 in boys, formally known as precocious puberty, is attributed to premature activation of the HPG axis. Doctors diagnosed it in a 2-year-old boy who showed signs of puberty including genital enlargement and growth of body hair.

His mother said these changes had started happening 6 months earlier, and a month after she had begun giving him cannabis oil. She had bought this online without prescription to ease his severe epilepsy, which hadn’t responded to any other treatment.

She explained that her son had had over 20 seizures every day since birth, and that these had become more frequent over time. He also had developmental…

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The use of medical cannabis for severe childhood epilepsy may be linked to early puberty, doctors have warned in the journal BMJ Case Reports after treating a 2 year old boy with the condition.

Some previously published studies have linked cannabis use to increased levels of the male hormone testosterone, raising the question of a possible dose-related effect as higher strength preparations are readily available, the report authors point out.

Research suggests that cannabis oil may help cut the risk of seizures in childhood epilepsy. But as yet, there’s no consensus on its impact on a trio of glands, known as the hypothalamo-pituitary-gonadal (HPG) axis.

This trio is responsible for the development and regulation of several of the body systems, including those for reproduction.

The start of puberty before the age of 9 in boys, formally known as precocious puberty, is attributed to premature activation of the HPG axis. Doctors diagnosed it in a 2-year-old boy who showed signs of puberty including genital enlargement and growth of body hair.

His mother said these changes had started happening 6 months earlier, and a month after she had begun giving him cannabis oil. She had bought this online without prescription to ease his severe epilepsy, which hadn’t responded to any other treatment.

She explained that her son had had over 20 seizures every day since birth, and that these had become more frequent over time. He also had developmental…



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